LACTORIL - Lactic ferments - Probiotic - Regenerating bacterial flora
CONTENT: maltodextrins 200 mg. Lactobacillus acidophvlus LA03 – DSM 17742 lyophilized 5 mg (bringing in living cells 500 milions), Lactobacillus bulgaricus LB22 – DSM 21471 lyophilized 50 mg (bringing in living cells 500 milions), Bifidumbacterium lactis BLC01 – DSM 17741, LMG23512 lyophilized 25 mg (bringing in living cells 250 milions), Calcium phosphate, Streptococcus thermophylus ST14 – DSM 19385 lyophilized 5 mg (bringing in living cells 500 milions). Anti-caking agents: vegetable magnesium stearate, silicon dioxide. Total amount in living cells: 1.75 milions.
Product included in the Italian Health Ministry food supplements Register, code 9775.
LACTORIL is a supplement based on lactobacillus, useful to re-establish the normal bacterial flora in the intestine.USE: 1 capsule a day.
WARNINGS: keep out of the reach of children under the age of three years. Do not exceed the recommended daily dose. The product should be used in the context of a varied and well-balanced diet and a healthy lifestyle.
NOTES: Probiotic, from the greek word pro Bios, it literally means "favorable to life", but the scientific definition that we commonly accept, is the one of the British researcher Fuller: probiotic is a living micro-organism that is able, once ingested, to exert a beneficial effect on the health of the host. Probiotics are the bacillus which are found in foods and that are introduced as drugs. Another way commonly used to define them is: lactic ferments. Above all, we are talking about Bifidobacteria and Lactobacillus (bacteria that use sugars as a source of energy and produce lactic acid) and some Enterococci, Streptococci and Saccharomyces. Currently we know more than 160 strains of them. The intestinal flora increases more and more when we moves away from the stomach to reach the colon, the most contaminated side. Its integrity is essential for the normal functioning of the digestive system.
FUNCTIONS OF THE INTESTINAL FLORA: The microflora contributes to the health of the body through different physiological mechanisms. An important function is to counteract the colonization of the portion of the pathogenic bacteria. Some "good" bacteria pass through the mucosal barrier and, in a normal subject, are killed in the lymph nodes and, because of this, thay does not spread. This mechanism stimulates the immune system to respond more quickly to pathogenic exogenous bacteria. At the end of their metabolism, the Bifidobacteria release some strong acids which lower the pH and exert an antibacterial action. They regularize the intestinal tract and thus contribute to eliminate the annoying constipation. All this we know thanks to the studies of the beginning of the century about bacterial flora and intestinal disturbances by the Russian biologist Prof. Ilya Ilyich Metchnikov, Nobel prize winner and researcher at the Institut Pasteur in Paris. He concluded that the birds survive longer than the mammals because unprovided with the colon. Just in this terminal portion of the intestine harmful bacteria develop, causing serious diseases and dramatically shortening the life of man. The scholar claimed to be able to keep the intestine free from harmful bacteria with a constant and regular use of lactic ferments. With his team, Metchnikov was able to separate, from a sample of Yogurt coming from a Bulgarian population famous for its longevity, the bacillus responsible for the fermentation, which from that moment onwards will be called bulgaric, or Lactobacillus bulgaricus. An important function of the bacterial physiological flora determines the maintenance of the vaginal environment normal conditions, keeping it acid. This task is, in fact, done mainly by Lactobacillus (especially the Lactobacillus acidophylus), which shall work to facilitate the absorption of essential nutrients and vitamins, in particular Vitamins of the B group and contribute to the production of vitamin K.
FUNCTIONS OF THE INTESTINAL FLORA: The microflora contributes to the health of the body through different physiological mechanisms. An important function is to counteract the colonization of the portion of the pathogenic bacteria. Some "good" bacteria pass through the mucosal barrier and, in a normal subject, are killed in the lymph nodes and, because of this, thay does not spread. This mechanism stimulates the immune system to respond more quickly to pathogenic exogenous bacteria. At the end of their metabolism, the Bifidobacteria release some strong acids which lower the pH and exert an antibacterial action. They regularize the intestinal tract and thus contribute to eliminate the annoying constipation. All this we know thanks to the studies of the beginning of the century about bacterial flora and intestinal disturbances by the Russian biologist Prof. Ilya Ilyich Metchnikov, Nobel prize winner and researcher at the Institut Pasteur in Paris. He concluded that the birds survive longer than the mammals because unprovided with the colon. Just in this terminal portion of the intestine harmful bacteria develop, causing serious diseases and dramatically shortening the life of man. The scholar claimed to be able to keep the intestine free from harmful bacteria with a constant and regular use of lactic ferments. With his team, Metchnikov was able to separate, from a sample of Yogurt coming from a Bulgarian population famous for its longevity, the bacillus responsible for the fermentation, which from that moment onwards will be called bulgaric, or Lactobacillus bulgaricus. An important function of the bacterial physiological flora determines the maintenance of the vaginal environment normal conditions, keeping it acid. This task is, in fact, done mainly by Lactobacillus (especially the Lactobacillus acidophylus), which shall work to facilitate the absorption of essential nutrients and vitamins, in particular Vitamins of the B group and contribute to the production of vitamin K.
THE EFFECTIVENESS OF LACTIC FERMENTS: Ideal for "regenerating" the intestine. Among its beneficial effects, in fact, we can remember: the "barrier" effect against pathogenic germs (that are cause of diarrhea and infections), the "immuno-competent" effect on the immune digestive system, which is also reflecting on the general immune system, the "cleaning-detoxification" effect that allows us to eliminate the toxins. According to some researchers and medical doctors the probiotics help us to mitigate some disorders and reduce infections of some dangerous bacillus. It's useful to eliminate the dysentery caused by bacteria or food imbalances; for regenerating the intestinal bacterial flora during and after antibiotic therapies. For treating the oral infections or skin disorders such as eczema, ulcers, and excoriations. To relieve chronic constipation, alleviate gastro-intestinal disorders. To compensate for vitamin deficiency and feed people with serious digestive problems. For replacing milk in cases of digestive allergic problems. Calming the nervous agitation. After the respiratory tract, the gastro-intestinal tract is the second largest human body surface corresponding to 250-400 m2, comparable in size to a tennis court. In the gastro-intestinal tract there are 10 indigenous bacteria for each cell of the body, for a total of 1014 bacteria compared to the 1013 cells that constitute our body. It has been estimated that the bacteria of the gastrointestinal tract can be divided every 20 minutes. This large number of new mutated bacteria allows the indigenous microflora to adapt quickly to the variation of the gastro-intestinal environment. In the course of a normal life, 60 tons of food pass through the digestive tract.
WHEN THE MICROFLORA IS COMPROMISED: Environmental factors can damage the Gastrointestinal flora: wrong feeding, age, use of drugs, stress, defective intestinal mobility. Alteration of the normal intestinal microflora reduces the defences of the organism, alters the existing balance between fermentative processes and putrefactive processes and encourages the development of potentially pathogenic germs. Modification of the normal flora, in addition to possible local infections, alters the metabolism of bile acids, the metabolism of the fatty acids and vitamin B12. This effects are made worse by a reduction in the gastric acidity, by a reduction of intestinal peristalsis and by intestinal stagnation, which contributes to form gas and to promote water retention. The bacteria that form the intestinal flora, work without intermission and produce gas that, in a reasonable share, makes the peristaltic intestinal contractions more effective so reducing the pressers repercussion that the only presence of liquids would generate during the digestive phase. However, in certain cases, we are used to accumulate in excess of them just in the digestive tract. This can occur for lack of absorption of the gas that is produced by the bacteria and by the trasformation process of foods that has already been inside of the intestine because of a too fast peristalsis. When this occurs, the gas tends to make hard and tense the abdomen and causes pain and bloating.
CANDIDA: when we talk about altered bacterial flora, we should also mention the presence, in our body, of the Candida albicans saprophytic. Normally it is present in the vaginal environment, with a pH between 5 and 4. Its real site is the small intestine mucosa. However, when the effectiveness of the immune system decreases because of the increase of exogenous and endogenous toxins, this mycete increases in a substantial way, causing problems for the health of the subject in question. The immune defenses may fall especially in the case of strong or frequent antibiotic treatments, or because of drugs that act on the Central Nervous System. For a infection by Candida, you can have syndromes due to chronic fatigue, hyperactivity, depression, anxiety, bulimia and anorexia. The huge increase in allergic and intolerant people to certain foods, is in relation to the modification that the candidiasis induces on immune responses and to the modifications of the small intestine mucosa permeability. USE OF ANTIBIOTICS: the probiotics, living microorganisms such as Lactobacillus acidophylus or Streptococcus thermophylus, serve to prevent the diarrhea that occurs as a complication during a treatment with antibiotics. The results of a study in the faculty of medicine of the Imperial College School of Medicine, published in the British Medical Journal, indicate that probiotics can be used to prevent diarrhea associated with the use of antibiotics. Further studies are needed to evaluate the effectiveness of probiotics alone in curing this diarrhea, once it is begun. In nine different clinical studies antibiotics and placebo or antibiotics and micro-organisms (probiotics) together have been given to people who needed of antibacterial therapy. The people who had taken antibiotics together with probiotics, from the beginning, have had an incidence of diarrhea significantly lower than those who had taken no microorganisms. The microorganisms used in the various studies were lactobacillus, or streptococci. The diarrhea caused by antibiotics is an frequent side effect of antibiotic therapy , even if often not well known. It is estimated that up to 30% of the antibiotic treated patients are subject to it. This problem may arise early, i.e. during the treatment itself or belatedly, i.e. up to two months after the suspension of the therapy. It may be of medium gravity, but also fulminans, as in the case of the pseudomembranous colitis, with shock or rupture of the intestine. This latter form usually affects very debilitated patients who are hospitalized for other serious diseases and subjected to an intense and prolonged antibiotic therapy. The diarrhea and dehydration that derives from it, is always dangerous, especially for elderly people, for those who are debilitated, however, for the immunocompromised persons and for children, especially those who are less than 10 years old and weigh less than 25 kilos. This complication occurs because of the alteration of the ecosystem that is present in the intestine. Antibiotics, through any path they are taken, not only through the oral one, but also intramuscular or intravenous, in addition to eliminate germs which are designated for, kill or alter the good intestinal flora, the one which lives in perfect harmony with our body and allows the maintenance of normal trophism of the intestine mucosa. It is calculated that for every gram of intestinal contents normally we host about 100 billion of intestinal useful microorganisms. When the balance of this multitude of germs come to be altered, other microorganisms, normally kept under control, can prevail and procur diarrhea. The normal metabolism of the intestinal flora can be altered even by the use of antibiotics, with problems in the metabolization of sugars and bile acids and consequent diarrheal syndrome. The antibiotics that frequently give this kind of problem are the penicillins, associations of penicillins and clavulonic acid and the cephalosporins. The microorganisms today available to prevent the onset of the diarrhea are many. The Lactobacillus acidophvlus, Lactobacillus bulgaricus, Bifidumbacterium bifidus and Streptococcus thermophilus were tested in various studies as anti dysentery remedies. Even if the researchers remind us that we need case studies on several patients to say a final word on the use of probiotics in this kind of diarrhea, however we now know that probiotics can prevent this complication during antibiotic therapy and from here the suggestion, especially for the people most under risk as the elderly and children, to assume probiotics already from the beginning of therapy with antibiotics. Up till now, there is not, in fact, any contraindications about the use of these agents.
WHEN THE MICROFLORA IS COMPROMISED: Environmental factors can damage the Gastrointestinal flora: wrong feeding, age, use of drugs, stress, defective intestinal mobility. Alteration of the normal intestinal microflora reduces the defences of the organism, alters the existing balance between fermentative processes and putrefactive processes and encourages the development of potentially pathogenic germs. Modification of the normal flora, in addition to possible local infections, alters the metabolism of bile acids, the metabolism of the fatty acids and vitamin B12. This effects are made worse by a reduction in the gastric acidity, by a reduction of intestinal peristalsis and by intestinal stagnation, which contributes to form gas and to promote water retention. The bacteria that form the intestinal flora, work without intermission and produce gas that, in a reasonable share, makes the peristaltic intestinal contractions more effective so reducing the pressers repercussion that the only presence of liquids would generate during the digestive phase. However, in certain cases, we are used to accumulate in excess of them just in the digestive tract. This can occur for lack of absorption of the gas that is produced by the bacteria and by the trasformation process of foods that has already been inside of the intestine because of a too fast peristalsis. When this occurs, the gas tends to make hard and tense the abdomen and causes pain and bloating.
CANDIDA: when we talk about altered bacterial flora, we should also mention the presence, in our body, of the Candida albicans saprophytic. Normally it is present in the vaginal environment, with a pH between 5 and 4. Its real site is the small intestine mucosa. However, when the effectiveness of the immune system decreases because of the increase of exogenous and endogenous toxins, this mycete increases in a substantial way, causing problems for the health of the subject in question. The immune defenses may fall especially in the case of strong or frequent antibiotic treatments, or because of drugs that act on the Central Nervous System. For a infection by Candida, you can have syndromes due to chronic fatigue, hyperactivity, depression, anxiety, bulimia and anorexia. The huge increase in allergic and intolerant people to certain foods, is in relation to the modification that the candidiasis induces on immune responses and to the modifications of the small intestine mucosa permeability. USE OF ANTIBIOTICS: the probiotics, living microorganisms such as Lactobacillus acidophylus or Streptococcus thermophylus, serve to prevent the diarrhea that occurs as a complication during a treatment with antibiotics. The results of a study in the faculty of medicine of the Imperial College School of Medicine, published in the British Medical Journal, indicate that probiotics can be used to prevent diarrhea associated with the use of antibiotics. Further studies are needed to evaluate the effectiveness of probiotics alone in curing this diarrhea, once it is begun. In nine different clinical studies antibiotics and placebo or antibiotics and micro-organisms (probiotics) together have been given to people who needed of antibacterial therapy. The people who had taken antibiotics together with probiotics, from the beginning, have had an incidence of diarrhea significantly lower than those who had taken no microorganisms. The microorganisms used in the various studies were lactobacillus, or streptococci. The diarrhea caused by antibiotics is an frequent side effect of antibiotic therapy , even if often not well known. It is estimated that up to 30% of the antibiotic treated patients are subject to it. This problem may arise early, i.e. during the treatment itself or belatedly, i.e. up to two months after the suspension of the therapy. It may be of medium gravity, but also fulminans, as in the case of the pseudomembranous colitis, with shock or rupture of the intestine. This latter form usually affects very debilitated patients who are hospitalized for other serious diseases and subjected to an intense and prolonged antibiotic therapy. The diarrhea and dehydration that derives from it, is always dangerous, especially for elderly people, for those who are debilitated, however, for the immunocompromised persons and for children, especially those who are less than 10 years old and weigh less than 25 kilos. This complication occurs because of the alteration of the ecosystem that is present in the intestine. Antibiotics, through any path they are taken, not only through the oral one, but also intramuscular or intravenous, in addition to eliminate germs which are designated for, kill or alter the good intestinal flora, the one which lives in perfect harmony with our body and allows the maintenance of normal trophism of the intestine mucosa. It is calculated that for every gram of intestinal contents normally we host about 100 billion of intestinal useful microorganisms. When the balance of this multitude of germs come to be altered, other microorganisms, normally kept under control, can prevail and procur diarrhea. The normal metabolism of the intestinal flora can be altered even by the use of antibiotics, with problems in the metabolization of sugars and bile acids and consequent diarrheal syndrome. The antibiotics that frequently give this kind of problem are the penicillins, associations of penicillins and clavulonic acid and the cephalosporins. The microorganisms today available to prevent the onset of the diarrhea are many. The Lactobacillus acidophvlus, Lactobacillus bulgaricus, Bifidumbacterium bifidus and Streptococcus thermophilus were tested in various studies as anti dysentery remedies. Even if the researchers remind us that we need case studies on several patients to say a final word on the use of probiotics in this kind of diarrhea, however we now know that probiotics can prevent this complication during antibiotic therapy and from here the suggestion, especially for the people most under risk as the elderly and children, to assume probiotics already from the beginning of therapy with antibiotics. Up till now, there is not, in fact, any contraindications about the use of these agents.